“This matchup is really annoying and pretty similar to other mage top lanes where it's hard to land your E, but because of her ultimate stunning you and her W grounding you making it to where you can't E, it can be a little bit harder to kill Casseiopeia, I like to go doran's shield and second wind in this matchup, and second item adaptive helm can be very strong in this matchup as well, early merc treads are also a great option. My best tip is to try to turn away when you think she is going to ultimate you to avoid the stun, you'll also have to have your W off when you do this, if you avoid her stun from ultimate you should be able to get an E on her if you land Q and pickup a kill. E flash can also secure you kills in this matchup.”
“Recommended: Sustain Runes & Teleport
Tips: Don't E In unless she wasted abilities. Passive shield her E's. Always try to dodge her Q. Turn around when Taunt durations ends to dodge her R if she's spamming it. Her W stops your R.”
“This matchup will either be very easy or very hard. Avoid her Q's when you go in for trades and at level 6, try not to use EQ to knock her up for your ult (unless she's at like 20% hp) because you will need to use E to dash through her and avoid getting stunned right after your ult. Just rush shieldbow as fast as possible!”
“Stupid Damage Early Game and Constant Kiting. Plus Hourglass are Broken which is the main reason you even see Mages Top-Lane.
Start with Corrupting Pot and Play Passive.
Parry her Ultimate/Turn Around(Comes with Practice)
Rush Mercury Treads. Get Quicksilver Sash if you don't want to get Mercury Treads against their Team comp.”
“She can dominate you by countering your skills with its stain.
Play defensively and dominate her in late game with your team.”
“A growing popular top laner because apparently hand to hand combat is too difficult for many. Her W is the biggest issue because you can't dash from it. It has a 24 second cooldown and she maxes it last so baiting it out is an effective strategy. Beating her ultimate is extremely hard since your engage is so linear. Your Q actually turns your back on her and will avoid the stun though timing this with the moment you turn is so hard, it's not worth leaning on. She will need to be shutdown early because her damage scaling is ridiculous and she heals like crazy when she takes Conqueror. ”
“One of the worst matchups for Mordekaiser. Your only hope is to ult her after she uses her miasma after which it should no longer be a factor and you might be able to edge out a kill. Cassiopeia is not only a complete counter, she is also braindead easy to play into Mordekaiser so you can't even rely on mistakes. She is the only lane I'd strongly recommed a Spectre's Cowl rush. There is not much you can do as she will dodge your E with her crazy movemetn speed. and if you do catch her, she will just Miasma you and walk away while chunking you down. Just play safe, don't get hit my her Qs EVER and try to chunk her down with a Q or two if you can. I'd save them for csing however. Ask for Jungle help if possible. Protobelt rush is good here. Wait for R with which you can kill her in rare cases. But if she is good, then its gonna be tough. D.Shield and Second Wind are a must.”
“Cassiopeia's main problem is her (Q) into her (E) spam which is impossible to avoid after being poisoned. Turn your back to her (R). If you are not familiar with her animations I would advise to check some Youtube videos related to it. Against her I recommend you to work on kiting and baiting out her poisons before trades. She is relatively fast for a champion that can't wear boots. The second you get struck by (Q) or (W) she will follow up with her (E) that can be spammed over and over, which really hurts! They tend to run Conqueror which heals her for a lot. You can't really dodge her (W), but you can build a bit more defensively while building into damage to make up for her damage.”
“She scales hard and she is fairly strong against Fiora early game. Attack when lvl 3 and and try to riposte her Q or any of her venom damage. She is very fast and good at kiting so try to land the riposte mainly for the slow. Predicting her ult with your riposte will come naturally. You can also see her turn around before the ult fairly easily.”
“TL;DR - ONE OF THE HARDEST MATCHUPS PERSONALLY FOR ME. DON’T EAT TOO MUCH POKE. SHE STRAIGHT UP BEATS YOU PRE-3. TRIPLE BEAD IS MANDATORY IF YOU TAKE TOO MUCH POKE. DSHIELD IS FOR IF YOU ARE A BETTER PLAYER. PHASE RUSH WORKS INTO HER BUT SO DOES CONQUEROR RESOLVE + SECOND WIND + UNFLINCHING. IF TAKING PHASE RUSH, TAKE NIMBUS CLOAK. BAIT HER TO WALK TOWARDS YOU. TRY TO PULL HER WHEN SHE IS ATTEMPTING TO Q YOU. RUN AWAY IF SHE LANDS Q. TRY TO FORCE FIGHT IF SHE MISSES Q. TRY NOT TO FACE HER ULTIMATE. DON’T STAND IN HER MIASMA. SPECTRE’S COWL/NEGATRON CLOAK. MERC BOOTS. ALL GOOD ITEMS VS HER.
Cassiopeia is a nightmare to deal with. She has movespeed, she has annoying poke, she has a difficult to counterplay ultimate AND, thanks to new Conqueror, heals up a LOT in all ins AND has early AP. Not to mention how she can ground you which stops you from using your ultimate. I’d recommend taking Conqueror with Second Wind and Unflinching if you wanna be safe. Resolve seconary with Nimbus can potentially work but it is SO risky. She will try to use her Q to poison you and then run you down with her Es. If you get hit by her poison, back off IMMEDIATELY. You will NOT win the fight. If she MISSES her poison, you have an opening to all in her. Try to walk back and then run towards her as she walks towards you to hit her abilities. If she takes Phase Rush, she will be more difficult to stick to but on the other hand, you will actually be able to kill her in an all in. If she takes Conqueror, her missing her Q is your only hope. She is weaker pre-6 so try to get on. Let her push the wave and then run her down with ghost. Having a Jungler helps a lot. Lastly, Force of Nature helps a lot into Cassio so if you are getting your ass beat, get an early Negatron Cloak and then build it into a FoN after Merc boots + Stridebreaker. If she is bad and allows you to kill him then just build normally and snowball on her. Be sure to give up minions and play the ranged matchup properly. You are gonna need almost ALL of your HP to beat her. Stridebreaker is REALLY great vs Cassio so if you are losing, try to play safe until you can get it.”