“This matchup is really annoying and pretty similar to other mage top lanes where it's hard to land your E, but because of her ultimate stunning you and her W grounding you making it to where you can't E, it can be a little bit harder to kill Casseiopeia, I like to go doran's shield and second wind in this matchup, and second item adaptive helm can be very strong in this matchup as well, early merc treads are also a great option. My best tip is to try to turn away when you think she is going to ultimate you to avoid the stun, you'll also have to have your W off when you do this, if you avoid her stun from ultimate you should be able to get an E on her if you land Q and pickup a kill. E flash can also secure you kills in this matchup.”
“Cassiopeia's main problem is her (Q) into her (E) spam which is impossible to avoid after being poisoned. Turn your back to her (R). If you are not familiar with her animations I would advise to check some Youtube videos related to it. Against her I recommend you to work on kiting and baiting out her poisons before trades. She is relatively fast for a champion that can't wear boots. The second you get struck by (Q) or (W) she will follow up with her (E) that can be spammed over and over, which really hurts! They tend to run Conqueror which heals her for a lot. You can't really dodge her (W), but you can build a bit more defensively while building into damage to make up for her damage.”
“She does damage, is fast and no cooldowns. Take Fleet or Grasp and trade when she misses her Q.
Best tip is take Fleet and TP, start Doran's Shield and just farm until Sheen and beg your jungler for ganks.”
“TL;DR - ONE OF THE HARDEST MATCHUPS PERSONALLY FOR ME. DON’T EAT TOO MUCH POKE. SHE STRAIGHT UP BEATS YOU PRE-3. TRIPLE BEAD IS MANDATORY IF YOU TAKE TOO MUCH POKE. DSHIELD IS FOR IF YOU ARE A BETTER PLAYER. PHASE RUSH WORKS INTO HER BUT SO DOES CONQUEROR RESOLVE + SECOND WIND + UNFLINCHING. IF TAKING PHASE RUSH, TAKE NIMBUS CLOAK. BAIT HER TO WALK TOWARDS YOU. TRY TO PULL HER WHEN SHE IS ATTEMPTING TO Q YOU. RUN AWAY IF SHE LANDS Q. TRY TO FORCE FIGHT IF SHE MISSES Q. TRY NOT TO FACE HER ULTIMATE. DON’T STAND IN HER MIASMA. SPECTRE’S COWL/NEGATRON CLOAK. MERC BOOTS. ALL GOOD ITEMS VS HER.
Cassiopeia is a nightmare to deal with. She has movespeed, she has annoying poke, she has a difficult to counterplay ultimate AND, thanks to new Conqueror, heals up a LOT in all ins AND has early AP. Not to mention how she can ground you which stops you from using your ultimate. I’d recommend taking Conqueror with Second Wind and Unflinching if you wanna be safe. Resolve seconary with Nimbus can potentially work but it is SO risky. She will try to use her Q to poison you and then run you down with her Es. If you get hit by her poison, back off IMMEDIATELY. You will NOT win the fight. If she MISSES her poison, you have an opening to all in her. Try to walk back and then run towards her as she walks towards you to hit her abilities. It helps to be near minions so that you can Q kill a minion and then run towards her with Phage Movement Speed. If she takes Phase Rush, she will be more difficult to stick to but on the other hand, you will actually be able to kill her in an all in. If she takes Conqueror, her missing her Q is your only hope. She is weaker pre-6 so try to get on. Let her push the wave and then run her down with ghost. Having a Jungler helps a lot. Lastly, Force of Nature helps a lot into Cassio so if you are getting your ass beat, get an early Negatron Cloak and then build it into a FoN after Merc boots + Stridebreaker. If she is bad and allows you to kill him then just build normally and snowball on her. Be sure to give up minions and play the ranged matchup properly. You are gonna need almost ALL of your HP to beat her. Stridebreaker is REALLY great vs Cassio so if you are losing, try to play safe until you can get it.”
“Ground gang. She slaps hard and her passive/phase rush means she can keep up with you. Dodge her Q and stay out of her W to have a fighting chance from my experience. Rylai's is really useful here to slow her down when she chases you.”
“This is a hard lane for Darius as Cassiopeia can poke from range and stay out of combat with Phase Rush. Make sure you dodge her Q as then she will have to waste her W to stop you from trading. Make sure that you start Dorans Sheild and rush Mercs treads! Your third item has to be an Adaptive helm!”
“3 of her skills are skillshot based. Will be up to you if this will be easy or hard match-up. Noxious Blast(Q) which is a poison blast, must be dodged to be able to trade. Miasma which is 5 second AOE that should be avoided as it can apply slow + grounding. Petrifying Gaze(R) can be avoided if you face away from Cassiopeia. (Recommended Items: Rylai's Scepter, Force of Nature or Cosmic Drive) (Sustained 1v1 Trades: Cassiopeia or Singed if he dodges all skillshots) (Outscaling Edge: Cassiopeia)”
“3 of her skills are skillshot based. Will be up to you if this will be easy or hard match-up. Noxious Blast(Q) which is a poison blast, must be dodged to be able to trade. Miasma which is 5 second AOE that should be avoided as it can apply slow + grounding. Petrifying Gaze(R) can be avoided if you face away from Cassiopeia. (Recommended Items: Spirit Visage, Force of Nature) (Sustained 1v1 Trades: Cassiopeia or Trundle if he dodges all skillshots) (Outscaling Edge: Even)”
“She scales hard and she is fairly strong against Fiora early game. Attack when lvl 3 and and try to riposte her Q or any of her venom damage. She is very fast and good at kiting so try to land the riposte mainly for the slow. Predicting her ult with your riposte will come naturally. You can also see her turn around before the ult fairly easily.”
“Not too bad early game, go in for a heavy trade level 1. Just make sure to dodge their Q early-game and you should win. Rush Mercury Treads to have the movement speed advantage and additional Tenacity. After level 6 it starts to get tricky, to win you'll need to either face away from their ult or use yours to dodge it, but both require good prediction, it's easier said than done. After they get their first 2 items it's very hard to play this matchup, they will run you down and you can't flash/R them when grounded. They melt you in team fights and run your team down too all while abusing Conqueror as a mage, it's not fun. In team fights focus your CC on them, and try to catch them out in sidelanes with your team if possible. Go Executioners and rush Abyssal Mask, or Spirit Visage if you have an enchanter.”