“Can barely touch you just afk farm and try to outroam her”
“Don't try to trade unless your jungler is coming soon. Look to farm and stay healthy so you can kill her with jungler. Go Doran's Shield, she should never be able to solokill you in lane. Always save E for her chain and make sure to account for her shields and movement speed before going for an execute. Take your time on using R. She makes the game a lot harder for you later on in the game, it's similar to Zilean but not as bad.”
“She had a great shield movement, cc and healing. makes ulting a nightmare and nullifies a lot of your dmg. While she probably will not kill you in lane she can poke you out and make late game hard. Take TP and hope. Just kinda a pain to play against. ”
“She can poke you a lot but after some items you'll be able to keep him pushed in, making her choose between minions and or rotating. Careful for her tether, it's an amazing gank setup.”
“Just play agressive at all times, only time you can lose is if she has consistent accuracy with her Qs. Dodge those and you should be fine. Once you have bork/wits end, you should be able to all in over and over. Mercs is good vs Karma if they have more cc's, but pref sorcs due to her vulnerability to getting solo'd. ”
“Fairly easy lane, she can never kill you but she is pretty hard to kill due to her healing and shields. Only way you really die in this lane is if your windwall is down and you get snared into RQ which should never happen. Dash out when she casts her E to get out of the tether range then go back in on her. Save ignite when going for an all in and before she heals with her RE. If she plays super safe you can just push her into tower and look for roams instead.”
“Just take dshield and fleet and just freely scale. Her poke will be annoying early but the setup should allow you to ignore it. She is a hard champion to kill but later on she has no hard cc for you which makes her very easy to deal with and kill her.”
“Start Doran + 2 Pots if 1) You think you can outplay her and hit your W's to generate a kill at levels 3-5 or 2) You think she will burst you down post 6 (get an extra ring).
Start Corrupting if you think you will not hit your W's (or you will get poked down) and you rely more on wave clear/spammy poke (you will be way more squisher but more durable -- this is recommended if you are sure you will not get hit by CC spells and instantly die).
Her only kill potential is by poking you down heavily (go biscuits if needed) or by using W to setup a gank for their jungler. Go for all ins if you want but in this matchup your main purpose is just to be the better damage dealer overall (which you will). Besides that play around the map and roam or try to help your jungler since you will vastly win any 2vs2 (especially if her empowered Q is on cd).”
“Dont play against this very much, but it is very high damage and very high healing. Any trade where she lands a R->Q is completely lost, especially in early levels. You may be tempted to overplay your lane since you feel like you are against a support but there is absolutely nothing troll about this pick. She has damage, wave clear and movespeed to keep up with the best of mids. Building normal is acceptable but if you see the opportunity, buying early grievous wounds can give you kill pressure, but otherwise I would just farm up and outperform her in lategame. Karma should generally not have kill pressure on you and not keep up with you late game but it really depends on the carries that she is buffing up.”
“Really annoying, if she wants to she can just push you in and tether then blast her load on you while you're chained up, no counterplay, proto helps a lot because you can just close the distance to her, a perfect karma won't let you close enough to damage her”